Research in Drug Development (RD3)
Microbiology, Bioorganic and Macromolecular Chemistry (MC)
My research are focused on :
The study of microorganisms, their virulence factors and drugs able to target them. My two main axes of research are human papillomaviruses (HPV) and mycobacteria. In virology, we are currently studying the regulation of the HPV-16 early gene expression and viral genome integration by various endogenic and iatrogenic factors. In mycobacteriology, our goals are to better characterize proteins involved in the synthesis of the waxy cell wall and to identify compounds able to inhibit the synthesis of this wall in order to target multidrug resistant Mycobacterium tuberculosis.
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Professor at the Faculty of Pharmacy (ULB) (2009-)
Scientist assistant for the Defense Ministry, DLD-Bio, Belgium(2009).
Head of the Papillomavirus Unit at the Institut Pasteur de Bruxelles, Belgium (2004-2008)
Post-doctoral fellow at the University of Amsterdam, AMC, Department of Virology, The Netherlands (1997-1998, 2000)
Post-doctoral fellow at the CLB, Department of Autoimmune Diseases, The Netherlands (1995-1996)
Post-doctoral fellow at the Weissmann Institute of Sciences, Department of Molecular Biology and Virology, Israel (1995)
Post-doctoral fellow at the Institut Pasteur de Bruxelles, Department of Virology, Belgium (1993-1994)
Post-doctoral fellow at the Imperial Cancer Research Fund, Department of Molecular Biology, United Kingdom (1992-1993)PhD in Medical Biology "Identification, by mutagenesis, of sequences required for the interaction of the human IL-6 with its receptor"Faculty of Medicine (ULB)(1992)
Teaching qualification (ULB)(1991)
PhD student - Institut Pasteur de Bruxelles (ULB)(1987-1992)