Bioingénieur en Biotechnologie, Université Libre de Bruxelles, 2004
Research Interests
Modelling the cell cycle by a stochastic automaton and applications to cancer chronotherapy
List of publications
2011
Altinok A, Gonze D,
Lévi F, Goldbeter A (2011) An automaton model for the cell cycle.
Royal Soc J Interface Focus1, 36-47.
Lévi F., Altinok A, Goldbeter A (2011)
Circadian rhythms and cancer chronotherapeutics.
In: Cancer Systems Biology, Bioinformatics and Medicine: Research and Clinical Applications
(Eds. F. Marcus and A. Cesario), Springer, Berlin (in press).
2009
Altinok A, Lévi F, Goldbeter A (2009) Identifying mechanisms of chronotolerance and chronoefficacy for the anticancer drugs 5-fluorouracil and oxaliplatin by computational modeling. Eur J Pharm Sci36, 20-38.
[Abstract]
[pdf file]
2008
Lévi F, Altinok A, Clairambault J, Goldbeter A (2008) Implications of circadian
clocks for the rhythmic delivery of cancer therapeutics. Phil Trans R Soc A366, 3575-3598.
[Abstract]
[pdf file]
2007
Altinok A, Lévi F, Goldbeter A (2007)
A cell cycle automaton model for probing circadian patterns of anticancer drug delivery.
Adv Drug Deliv Rev59, :1036-53. (doi:10.1016/j.addr.2006.09.022).
[Abstract]
[pdf file]
Altinok A, Lévi F, Goldbeter A (2007)
Optimizing temporal patterns of anticancer drug delivery by simulations of a cell cycle automaton.
In: "Biosimulation in Drug Development", M. Bertau, E. Mosekilde and H.V. Westerhoff Eds., Wiley-VCH, pp. 275-297.
[Abstract]
[pdf file]