Atilla Altinok

Former Collaborator

Unité de Chronobiologie Théorique
Faculté des Sciences
Campus Plaine, C.P. 231
Université Libre de Bruxelles
1050 Brussels, Belgium

Phone: (32) 02 6505817
Fax: (32) 02 6505767

Photo of A. Altinok


  • Bioingénieur en Biotechnologie, Université Libre de Bruxelles, 2004

    Research Interests

  • Modelling the cell cycle by a stochastic automaton and applications to cancer chronotherapy

    List of publications


  • Altinok A, Gonze D, LÚvi F, Goldbeter A (2011) An automaton model for the cell cycle. Royal Soc J Interface Focus 1, 36-47.
  • LÚvi F., Altinok A, Goldbeter A (2011) Circadian rhythms and cancer chronotherapeutics. In: Cancer Systems Biology, Bioinformatics and Medicine: Research and Clinical Applications (Eds. F. Marcus and A. Cesario), Springer, Berlin, pp. 381-407.


  • Altinok A, Lévi F, Goldbeter A (2009) Identifying mechanisms of chronotolerance and chronoefficacy for the anticancer drugs 5-fluorouracil and oxaliplatin by computational modeling. Eur J Pharm Sci 36, 20-38. [Abstract] [pdf file]


  • LÚvi F, Altinok A, Clairambault J, Goldbeter A (2008) Implications of circadian clocks for the rhythmic delivery of cancer therapeutics. Phil Trans R Soc A 366, 3575-3598. [Abstract] [pdf file]


  • Altinok A, Lévi F, Goldbeter A (2007) A cell cycle automaton model for probing circadian patterns of anticancer drug delivery. Adv Drug Deliv Rev 59, :1036-53. (doi:10.1016/j.addr.2006.09.022). [Abstract] [pdf file]
  • Altinok A, Lévi F, Goldbeter A (2007) Optimizing temporal patterns of anticancer drug delivery by simulations of a cell cycle automaton. In: "Biosimulation in Drug Development", M. Bertau, E. Mosekilde and H.V. Westerhoff Eds., Wiley-VCH, pp. 275-297. [Abstract] [pdf file]

    ULB - UTC: A. Altinok / Revised :