IRIBHM Microarray Data

• Clicking on the links will most likely open them in your web browser. You may save them on your hard drive by right-clicking on the links and select "Save the link as..." in the pop-up menu.
• Data are presented as csv files (comma separated plain text format), compressed with gzip. The csv format is recognized by any spreadsheet software, any compression utility will handle gzip, both formats are nonproprietary.
• Column names finishing with ".M" are log2-ratios, columns finishing with ".A" are log2 averages of the red and green channels.
• Missing data are labelled "NA".
• The references to be cited are indicated in the header of each section below.
• This page is maintained by Vincent Detours.

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van Staveren W.C.G., Weiss Solís D., Delys L., Duprez L., Andry G., Franc B., Thomas G., Libert F., Dumont J.E., Detours V., Maenhaut C., Human thyroid tumor cell lines derived from different tumor types present a common dedifferentiated phenotype. Cancer Res., 2007, 67(17):8113-20.

1. van-staveren-cancer-res-2007-1.csv, thyroid tumor-derived cell lines on IRIBHM custom slides

2. van-staveren-cancer-res-2007-2.csv, 16 papillary thyroid carcinomas, a follicular thyroid carcinoma and a follicular thyroid adenoma on IRIBHM custom slides

3. van-staveren-cancer-res-2007-3.csv, 3 anaplastic thyroid carcinomas, 3 papillary thyroid carcinomas, a pool of normal thyroid tissues, and 3 normal tissues adjacent to the 3 papillary thyroid tumors in Affymetrix HGU133 Plus 2.0 chip.

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Detours, V., Delys, L., Libert, F., Weiss Solís, D., Bogdanova, T., Dumont, J. E., Franc, B., Thomas, G. & Maenhaut, C., (2007), Genome-wide Gene Expression Profiling Suggests Distinct Radiation Susceptibilities in Sporadic and Post-Chernobyl Papillary Thyroid Cancers, British J. Cancer 97, 818-25.

1. Data available from the Gene Expression Omnibus (www.ncbi.nlm.nih.gov/geo), accession number GSE3950.

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Delys, L., Detours, V., Franc, B., Thomas, G., Bogdanova, Tronko, M., T., Libert, F., Dumont, J. E. & Maenhaut, C., (2007), Gene expression and the biological phenotype of papillary thyroid carcinomas, Oncogene, 26(57), 7894-903.

1. Data available from the Gene Expression Omnibus (www.ncbi.nlm.nih.gov/geo), accession number GSE3950.

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van Staveren, C. G., Weiss, D., Delys, L., Venet, D., Cappello, M., Andry, G., Dumont, J. E., Libert, F., Detours, V. & Maenhaut, C., (2006), Gene Expression in TSH-treated Human Thyrocytes and Autonomous Adenomas: Suppression of Negative Feedbacks in Tumorigenesis, Proc. Nat. Acad. Sci. USA 103, 413–418.

1. pnas-van-staveren-2006.csv.gz, TSH time series and autonomous adenoma pool data on IRIBHM custom slides

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Wattel, S., Mircescu, H., Venet, D., Burniat, A., Franc, B., Frank, S., Andry, G., Van Sande, J., Rocmans, P., Dumont, J. E., Detours, V. & Maenhaut, C., (2005), Gene Expression in Thyroid Autonomous Adenomas Provides Insight on their  Physiopathology, Oncogene 24, 1545-52.

1. oncogene-wattel-2005-1.csv.gz, autonomous adenoma on Perkin-Elmer NEN slides

2. oncogene-wattel-2005-2.csv.gz, autonomous adenoma pool on VIB Human 5K slides series

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Detours, V., Wattel, S., Venet, D., Hutsebaut, N., Bogdanova, T., Tronko, M. D., Dumont, J. E., Franc, B., Thomas, G. & Maenhaut, C., (2005), Absence of a Specific Radiation Signature in Post-Chernobyl Thyroid Cancers, British J. Cancer 92, 1545-1552.

1. bjc-detours-2005-1.csv.gz, patient-wise expression on Perkin-Elmer NEN slides

2. bjc-detours-2005-2.csv.gz, pool expression for sporadic PTC samples, VIB Human 5K slides series

3. bjc-detours-2005-3.csv.gz, pool expression for post-Chernobyl PTC samples, VIB Human 23K slides

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Goffard JC, Jin L, Mircescu H, Van Hummelen P, Ledent C, Dumont JE, Corvilain B., (2004), Gene expression profile in thyroid of transgenic mice overexpressing the adenosine receptor 2a, Mol Endocrinol. 18(1):194-213.

1. me-goffard-2004-1.csv.gz, a2r data on VIB Mouse 5K slide series. Also available on NCBI’s GEO, accession GSE780.

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