Department of Pharmacotherapy and Pharmaceutics (DPP)
γδ T cells are unconventional T cells that express a γδ T cell receptor (TCR) on their cell surface instead of an αβ TCR as on conventional αβ T cells. γδ T cells can have several roles, including protection against infections and tumors. The general approach of our current research is to obtain insight into human γδ T cells by applying sophisticated molecular biological techniques on clinical samples. Important in vivo findings are then further investigated in vitro in order to understand molecular mechanisms. A main focus of our research is the role and ontogeny of human γδ T cells in early life. This research is leading to novel targets (molecules, cells) for pharmacotherapy.
TOP 10 RECENT ARTICLES:
Since 2012: senior lecturer; principle investigator at the Department of Pharmacotherapy and Pharmaceutics, ULB.
2006-2012: post-doctoral research fellow at the Institute for Medical Immunology, Université Libre de Bruxelles (ULB)
2003-2006: post-doctoral research fellow at the laboratory of Prof. Adrian Hayday at the Peter Gorer Department of Immunobiology, King’s College London, UK.
2003: Ph.D. thesis: “Tumor cell killing by hepatic natural killer cells”, at the VUB (Vrije Universiteit Brussel (VUB), Free University of Brussels)