Selected publications of Prof. Guy Rutter

 

1. Gallo, A, Giulio, C, Pinton P, Elisabetta,I, Ellen, M, Rutter G.A., Rizzuto R., Semplicini, A., Avogaro, A, Metformin Prevents Glucose-Induced PKCbeta2 Activation In Human Umbilical Vein Endothelial Cells Through an Antioxidant Mechanism. Diabetes, 54(4):1123-31, 2005. [PubMed]

2. Varadi, A., Tsuboi, T., Rutter, G.A. Myosin Va transports dense core vesicles in pancreatic MIN6 Beta-cells. Mol Biol Cell 16(6):2670-2680, 2005. [PubMed]

3. Ravier, M.A. and Rutter G.A. Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic Beta-cells. Diabetes 54, 1789-1797, 2005. [PubMed]

4. Tsuboi, T., Ravier, M.A., Xie, H., Ewart, M-A, Gould, G.W., Baldwin, S.A., Rutter, G.A. The mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis. J. Biol. Chem. 280 (27) 25565-25570, 2005. [PubMed]

5. Richards, S.K., Parton, L.E., Leclerc, I., Rutter, G.A., Smith, R.M. Over-expression of AMP-activated protein kinase impairs pancreatic Beta-cell function in vivo. J Endocrinol, 187, 225-235, 2005. [PubMed]

6. Storto, M., Capbianco, L., Battaglia, G., Molinaro, G, Gradini, R., Riozzi, B., Mitchell, K.J., Bruno, V., Vairetti, M.P., Rutter, G.A., and Nicoletti, F. Insulin secretion is under the control of Type-5 metabotropic glutamate receptors. Mol Pharmacol 69(4):1234-41, 2006. [PubMed]

7. Tsuboi, T, Ravier, M.A., Parton, L.E. and Rutter, G.A. Sustained exposure to elevated glucose concentrations modifies glucose signaling and the mechanics of secretory vesicle fusion in primary rat pancreatic Beta-cells. Diabetes, 55(4):1057-1065, 2006. [PubMed]

8. Varadi, A., Grant, A, McCormack, M, Nicholson, T. Magistri, M, Kathryn J. Mitchell, KJ, Halestrap A.P., Yuan, H, Schwappach, B, and Rutter, G.A. Intracellular ATP-sensitive K+ channels in mouse Beta-cells: against a role in organelle cation homeostasis. Diabetologia 49(7):1567-77 (2006); [Epub ahead of print] [PubMed]

9. Parton, L, McMillen, PJ, Shen, Y, Docherty, E, Sharpe, E, Diraison, F, Briscoe, CP, Rutter GA. Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis. Am J. Physiol. 291(5):E982-94, 2006. [PubMed]

10. Motakis, E.S., Nason, G.P., Fryzlewicz, P. and Rutter, G.A. Variance stabilization and normalization for one colour microarray data using a data-driven multiscale approach. Bioinformatics 22(20):2547-53 (2006). [PubMed]

11. Bell, C.J., Bright, NA, Rutter, G.A., Griffiths, E.J. ATP regulation in adult cardiomyocytes: time resolved decoding of rapid mitochodrial calcium spiking imaged with targeted photoproteins. J Biol Chem, 281(38):28058-67 (2006). [PubMed]

12. Rencuerel, F, Kaufmann, M, Stroka, D, Foretz, M, Viollet, B, Leclerc, I., daSilvaXavier, G, Rutter, G.A., Meyer, UA Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver. Mol Pharmacol 70(6):1925-34 (2006). [PubMed]

13. daSilvaXavier, G., Rutter, G.A. [joint first authors] Diraison, F., Andreolas, C, and Leclerc, I. Carbohydrate-response element binding protein (ChREBP) binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic MIN6 Beta-cells J Lipid Res. 47(11):2482-91 (2006). [PubMed]

14. McKinnon, C.M., Ravier, M.A. and Rutter, G.A. FoxO1 is required for preproglucagon gene expression and regulated glucagon release from pancreatic Alpha-(TC1-9) cells. J Biol Chem, 281(51):39358-69 (2006). [PubMed]

15. Mountjoy, P.D., Bailey, S.J. and Rutter G.A. Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity. Diabetologia 50(1):168-77 (2007). [PubMed]

16. Bailey, S.J. Ravier, M.A., Rutter, G.A. Glucose-dependent regulation of GABA-A receptor expression in mouse pancreatic Beta-cells. Diabetes 56(2):320-7 (2007). [PubMed]

17. Guillemain, G., Filhouland, G., daSilvaXavier, G, Rutter, G.A., Scharfmann, R. Glucose is necessary for embryonic endocrine cell differentiation. J Biol Chem. 282(20):15228-37 (2007). [PubMed]

18. Baroukh, N, Ravier, M.A., Loder, M.A., Hill, A.V., Bounacer, A., Scharfmann, R., Rutter, G.A., Van Obberghen E. MicroRNA-124a2 regulates foxa2 expression and intracellular signaling in pancreatic Beta-cell lines.  J Biol Chem, 282(27):19575-88 (2007). [PubMed]

19. Otonkoski, T., Jiao, H., Kaminen-Ahola, N., Tapia-Paez, I., Ullah, M.S., Parton, L.E., Schuit , F., Quintens, R., Sipilä, I., Mayatepek, E., Meissner, T., Halestrap, A.P., Rutter G.A. and Kere, J. Physical exercise-induced hyperinsulinemic hypoglycemia caused by failure of monocarboxylate transport 1 silencing in pancreatic beta cells. Am J Hum Genet. 81(3):467-74 (2007). [PubMed]

20. Jacquet, S., Zarrinpashneh, E., Chavey, A., Leclerc,I., Cohen, P, Rutter,G.A., Bertrand,L, Marber, MS. The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia. Cardiovas Res., In press (2007). [PubMed]

21. Zatyka M, Ricketts, C, da Silva Xavier, G, Minton, JA, Fenton, S, Hofmann-Thiel, S, Rutter G.A., and Barrett TG. Sodium-potassium ATPase beta 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum (ER) protein involved in ER stress, in press at Hum Mol Genet Sep 07. [PubMed]

22. Barrow, SL, Voronina, S., daSilvaXavier, G., Chvanov, M., Petersen, O.H, Gerasimenko, O, Rutter, G.A., Tepikin, A. ATP depletion synchronously inhibits store-dependent calcium influx, calcium extrusion and calcium release from internal stores but not bile-induced calcium responses. Implications for acute pancreatitis. Pflugers Arch. 2007 Oct 20; [Epub ahead of print] [PubMed]