Selected publications of Dr. Gavin Kelsey 

 

PUBLICATIONS, Research

1. Plagge, A., Gordon, E., Dean, W., Boiani, R., Cinti, S., Peters, J. and Kelsey, G. (2004) The imprinted signalling protein XLαs is required for postnatal adaptation to feeding. Nat. Genetics 36, 818-826. [PubMed]

2. Ma, D., Shield, J. P. H., Dean, W., Leclerc, I., Knauf, C., Burcelin, R., Rutter, G. A. and Kelsey, G. (2004) Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus (TNDM) locus. J. Clin. Invest. 114, 339-348.  [PubMed]

3. Plagge, A., Isles, A. R., Gordon, E., Humby, T., Dean, W., Gritsch, S., Fischer-Colbrie, R., Wilkinson, L. S., and Kelsey, G. (2005) The imprinted Nesp55 influences behavioral reactivity to novel environments. Mol. Cell. Biol. 25, 3019-3026.  [PubMed]

4. Constancia, M., Anglioni, E., Sandovici, I., Smith, P., Smith R. J., Kelsey, G., Dean, W., Ferguson-Smith, A.C., Sibley, C.P., Reik, W. and Fowden, A. L. (2005) Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc. Natl. Acad. Sci. 102, 19219-19224. [PubMed]

5. Arnaud, P., Hata, K., Kaneda, M., Li, E., Sasaki, H., Feil, R, and Kelsey, G. (2006) Stochastic imprinting defects in the progeny of Dnmt3l-/- females. Hum. Mol. Genet. 15, 589-598. [PubMed]

6. Williamson C. M., Turner, M. D., Ball, S. T., Nottingham, W. T., Glenister, P., Fray, M., Plagge, A., Powles-Glover, N., Kelsey, G., Maconochie, M. and Peters, J. (2006) Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster. Nat. Genetics 38, 350-355. [PubMed]

7. Monk, D., Arnaud, P., Apostolidou, S., Hills, F.A., Kelsey, G., Stanier, P., Feil, R. and Moore, G.E. (2006) Limited evolutionary conservation of imprinting in the human placenta. Proc. Natl. Acad. Sci. 103, 6623-6628. [PubMed]

8. Xie, T., Plagge, A., Gavrilova, O., Pack, S., Jou, W., Lai, E.W., Frontera, M., Kelsey, G. and Weinstein, L.S. (2006) The alternative stimulatory G protein α-subunit XLαs is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice. J. Biol. Chem. 281, 18989-18999. [PubMed]

9. Ruf, N., Bähring, S., Galetzka, D., Pliushch, G., Luft, F.C., Nürnberg, P., Haaf, T., Kelsey, G. and Zechner, U. Sequence-based bioinformatic prediction and QUASEP identify genomic imprinting of the KCNK9 potassium channel gene in mouse and human. Hum. Mol. Genet., (Epub ahead of print Aug. 17). [PubMed]

PUBLICATIONS, Reviews

1. Constância, M., Kelsey, G. and Reik, W. (2004) Outlook: news and views feature: Resourceful Imprinting. Nature 432, 53-57. [PubMed]

2. Plagge, A. and Kelsey, G. (2006) Imprinting the Gnas locus. Cytogenetic and Genome Res. 113, 178-187. [PubMed]

3. Plagge, A., Kelsey, G. and Geramin-Lee, E. L. Physiological functions of the imprinted Gnas locus and its protein variants Gαs and XLαs in human and mouse. J. Endocrin. (subm.)

PUBLICATIONS, Book Chapters

1. Kelsey, G. Genomic imprinting – roles and regulation in development. In: Development of the Pancreas and Neonatal Diabetes; Endocr. Dev. Vol. 12, pp99-112; Scharfmann R. and Hamilton-Shield, J. eds., S. Karger Publishers, Basel. 

2. Frontera, M., Dickins, B., Plagge, A. and Kelsey, G. Imprinted genes, postnatal adaptations and enduring effects on energy homeostasis. In: Genomic Imprinting, Wilkins J. ed., Landes Bioscience, Georgetown, TX. (in press).